Covid vaccines less effective against Delta variant: Pfizer Inc. And the Bioentech SE’s messenger RNA vaccine lost its effectiveness in the first 90 days after full vaccination, but that shot and what Astrogeneneka Plc did still prevented most Covid infections.
Vaccines against Covid-19 against the Delta variant are less effective, and the results of a large UK study provide an incentive for booster shots for people who have been fully vaccinated.
Pfizer Inc. And the Bioentech SE’s messenger RNA vaccine lost its effectiveness in the first 90 days after full vaccination, but that shot and what Astrogeneneka Plc did still prevented most Covid infections. When vaccinated people become infected with Delta, they have the same virus levels in their body as those without shots in their body, the Centers for Disease Control and Prevention backs up a recent assessment.
Although there is not enough supply for the first vaccinations in countries around the world, the results are likely to fuel calls to give booster shots to those who have been fully vaccinated. Pfizer-Bioentech or Modernna Inc. The U.S. said Wednesday that Americans receiving two doses can get a third after eight months. UK officials are still deciding how widely to give boosters. In Israel, which began giving a third dose of Pfizer-Biotech earlier this month, initial results show it is 86% effective for people over 60.
The UK survey, conducted by the University of Oxford and the Office for National Statistics and published in the preprint on Thursday, analyzed over 3 million PCR tests from a random sample for a detailed picture of the infection patterns as the delta became a dominant variant. Year.
“Here we look at real-world data on how two vaccines work better than clinical trial data, and how data sets obscure the effect of both the Delta variant Pfizer and the Astrogenica Jabs,” said Simon Clark, associate professor of cellular microbiology at the University of Reading.
About four-and-a-half months after the second dose, Pfizer’s shot was probably on par with Astra in preventing infections with a high viral load, said Coin Powells, a senior Oxford researcher who led the study. There was no statistically significant difference in the effect of the Astra shot over time.
Sarah Walker, a professor of medical statistics and epidemiology at Oxford, who led the study, said the results cast more doubt on the possibility of herd immunity being achieved through vaccines.
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“It is hoped that most people who are not vaccinated will be saved by being vaccinated,” Walker said. “The high level of virus we see in these vaccinated people is consistent with the fact that people who are not vaccinated are at higher risk, I fear.”
An important part of the puzzle that is still unseen is data showing how vaccines protect against Covid’s serious cases and hospitalizations over time, said Penny Ward, a visiting professor of pharmaceutical medicine at King ‘College London. Study. The research could also support giving a booster dose of the mRNA vaccine to people who have received an Astra shot using a different technology, Ward said in a statement. They also drive home the need for better Covid treatments, she said.
“The vaccine is not fully protected against infection with the Delta variant,” Ward said. “The low incidence of hospitalization seen to date suggests that in this case, at the very least, vaccines are protecting individuals from developing severe covid.”